CRAIG HEACOCK, M. ) Littrell RA, carisoprodol use hayes LR, Stillner V. (3) This case report highlights this potential danger. Electrolytes, liver function tests, complete blood count, vitamin B12, folate, and thyroid-stimulating hormone levels were within normal limits. Discussion Biochemically, skeletal muscle relaxants are a diverse group of drugs. He denied recent use of alcohol or other drugs, symptoms of carisoprodol use aura or a postictal state, recent head injury or illness, or overuse of his prescribed medications. Before the patient could be seen again in the office, he died of cardiac arrhythmia due to chronic drug abuse. The generic market for Able’s newly approved drug, mainly used as a muscle relaxant and for muscle spasms, is estimated to be $260 million by IMS Data. Later that day, another tommunity pharmacist telephoned to confirm the prescription, because the patient had received this medication from two other physicians. We carisoprodol use suspected that he was experiencing amnestic periods secondary to his use of multiple psychoactive medications. Soma carisoprodol use is a registered trademark of WallaceLaboratories. The Letter to the Editor, "Tolerance and Dependence Risk with the Use of Carisoprodol," by Craig Heacock, M. Carisoprodol use, and Mark S. (2) A recent survey (3) of physicians indicates that carisoprodol’s metabolism to a barbiturate is not widely appreciated, which likely contributes to its continued popularity. A small but growing amount of literature is available regarding morbidity associated with the use of carisoprodol, including respiratory compromise (1) and vehicle crashes. We have not carisoprodol use stopped our R&D efforts. [7] The extent to which skeletal muscle relaxants are abused is unclear, since only limited published data are available. Providence, RI 02908-4799 The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or Carisoprodol use as reflecting the views of the Department of Veterans Affairs. Robert Cusick, Chairman and Chief Executive Officer of carisoprodol use able Laboratories, Inc. Two months later, the patient requested another refill of the carisoprodol prescription. The second sentence in the first paragraph of the letter should have stated that meprobamate is a schedule IV drug that has a long history of abuse and exhibits cross-tolerance to barbiturates.