At press time, those changes had been made in the labels for venlafaxine effexor and wellbutrin (effexor and Effexor XR), nefazodone (Serzone), bupropion (Wellbutrin, Zyban), citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), and paroxetine (Paxil). Patents should not stop treatment without first talking to their doctors. Warnings about the potential for suicidality and worsening of depression during treatment with antidepressants for major depressive disorder have begun to appear in the label of antidepressant drugs, in response to a request made by the Food and Drug Administration in March. Within the switch options, the response and remission rates as measured by the Hamilton Rating Scale for Depression (HRSD) and the Quick Inventory of Depressive Symptomatology were similar (HRSD remission rates of 21% for bupropion SR, 18% for sertraline, and 25% for venlafaxine XR). The lack of an economic interest also precludes any systematic follow-up on drugs once they’re approved by the FDA. The warnings came after an FDA advisory panel heard emotional testimony last month from dozens of patients and family members who effexor and wellbutrin blame the drugs for suicide attempts, suicides and violent acts by children who had been talking them. In August 2004, the agency warned that newborns could be harmed if their mothers were taking a selective serotonin reuptake inhibtor (SSRI), or a newer (atypical) antidepressant during the third trimester of pregnancy. Despite the new advisory, don’t stop taking your effexor and wellbutrin antidepressant. At the meeting, even researchers and academic psychiatrists who were well-known proponents of psychiatric medication for children pleaded for transparency in research findings. Our hope is that the new language and labeling will result in closer observation of patients who are being prescribed these drugs, said Dr. In October, all the antidepressants known as SSRIs except Prozac were banned because studies from the United States did not show they were effective in treating children with depression but did show they were twice as likely as placebos to lead to suicide. Mylan Laboratories has filed suit against Procter & Gamble and Watson Pharmaceuticals over an agreement under which Watson distributes an authorized generic version of P&G’s Macrobid. More than a decade ago, similar concerns over Prozac were beaten down in U. (Begin effexor and wellbutrin optional trim) (End optional trim) Dr. The effexor and wellbutrin public health advisory containing the new label warnings is available online at www. Gov/cder/drug/antidepressants/. WASHINGTON — The Food and Drug Administration warned doctors, patients and their families Monday to watch closely for signs of deepening depression and possible suicide among those taking 10 popular antidepressants. Therefore, therapy should be evaluated, and medications may need to be discontinued, when symptoms are severe, abrupt in onset, or were not part effexor and wellbutrin of the patient’s presenting symptoms.